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Neuroscience & Mental Health How Psilocybin Changes the Brain: What New Research Actually Shows Written by Joseph Santiago For decades, psychedelics lived in the shadows of science. Dismissed as dangerous counterculture relics, substances like psilocybin — the psychoactive compound found in magic mushrooms and truffles — were largely absent from serious medical conversation. But today, […]

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Written by Sarah McGruddy Source & Study Reference https://doi.org/10.1038/s41598-026-38091-9 Garcia-Romeu, A., Naudé, G. P., Rebman, A. W., So, S., Yaffe, A., Geithner, I., … & Aucott, J. N. (2026). Pilot study of psilocybin in patients with post-treatment lyme disease. Scientific reports, 16(1), 7497. Introduction: Psilocybin as a Therapeutic Tool Psilocybin (the psychoactive compound found in […]

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Before It Had a Name: The Long, Strange History of Microdosing From Mesoamerican ritual to Silicon Valley boardrooms to double-blind placebo trials — the story of humanity’s quietest psychedelic experiment is older, stranger, and more scientifically interesting than you think. By Joseph Santiago Somewhere in Mesoamerica, thousands of years before the word “microdose” existed, someone […]

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What Longevity Research, Neuroscience, and Ancient Mysticism May Be Revealing About Consciousness In the past decade, scientists have begun exploring an intriguing question: could psychedelics help protect the brain from aging? New research into psychedelics and brain aging is emerging from institutions such as Johns Hopkins University, Imperial College London, and NYU Langone Health. What […]

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Understanding How Psychedelics Work: From Mystical Moments to Modern Science Have you ever wondered how psychedelics actually work right before munching on a handful of magic mushrooms? You’re not alone. For centuries, indigenous cultures across the globe—from the Mazatec people of Mexico with psilocybin mushrooms, to Amazonian shamans with ayahuasca, to Native Americans with peyote—have […]

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