Do you find yourself yawning excessively whenever you take mushrooms? This might have probably ruined your psychedelic experience in the past, and you are wondering what could be wrong. Worry no more because we will highlight the reasons why you keep yawning and how to stop it. So, continue reading to find out more.

Statistics show that virtually everyone using psychedelic mushrooms testify to frequent and uncontrollable yawning. It is basically one of the noticeable parts of the entire psychedelic experience. For beginners, this can be a surprising side effect as it lacks an

y logical explanation since they are not bored or sleepy. However, the yawning persists.

There’s no scientific justification for this, and there are many theories about the cause of shrooms-induced yawning. However, there are empirical evidence highlighting remedies for the side effect.

Should You Be Worried About Yawning During a Shroom Trip?

Yawning is a common thing during a psychedelic trip, and with that, you shouldn’t be worried. It usually occurs during the come-up phase of the trip. This is a period when your digestive system starts the conversion of psilocybin to psilocin. It’s worth mentioning that psilocin is the compound that triggers the psychedelic effect.

Psilocin and psilocybin both interact with serotonin receptors within the brain, and they particularly have a high affinity for 5-HT2A subtype receptors. Studies in rats show that psilocybin reacts with receptors in the hub regions of the brain responsible for integrating sensory experiences. This is a possible reason for effects like synesthesia, tasting sounds, hearing colors, or a general altered sensory experience people get after tripping on shrooms.

If you consume larger doses, you’re likely to experience longer conversion, which further extends the side effects and come-up. The effects of moderate doses usually last between 3 to 6 hours, and after the psilocybin to psilocin conversion ends, you will experience yawning.

You might find this annoying, but it’s advisable to see it as a reassurance that you have taken a potent psychedelic mushroom. It’s also a potential indication that you are close to the take-off of the psychedelic journey. If you want to enjoy a positive experience and reduce the risk of having a bad trip, you’ll need to prepare your mind and body ahead.

The process of preparing involves reflecting on your goals and creating an environment you are familiar with and comfortable with. This environment is often referred to as set and setting. With this practice, you will be able to enhance the experience you get and avoid negative effects.

Yawning: Why Do We Experience It?

People usually experience yawning in response to different situations, and this makes it difficult to determine its cause. For example, you’re likely to yawn excessively if you’re in a boring presentation or class. You might also yawn during a stressful situation or after taking medication.

Even though there are many studies about yawning, there’s no scientific conclusion about its actual cause. However, there are many hypotheses indicating why it occurs, and here’s a quick overview of these hypotheses.

Communication Hypothesis

There are studies that highlight yawning as a way for people to increase their critical consciousness and diminish communication. Critical consciousness is basic awareness of the environment. Usually, repetitive or boring stimuli tend to blunt it out. This basically explains why yawns are contagious since they increase the consciousness of other people.

Respiratory Hypothesis

According to the respiratory hypothesis, yawning is a mechanism that allows the body to oxygenate itself. The rise of CO2 levels in the blood causes massive oxygen inspiration and CO2 exhalation. This is automatically restored by a yawn, and the oxygen levels because restored automatically.

This story was prevalent in the 18th century after Johannes de Gorter proposed it. However, it was proven to be false in 1987. In a study, Robert Provine showed that humans don’t yawn excessively after exposure to high CO2 levels or physical exercise.

Brain Cooling Hypothesis

The hypothesis highlights that yawning is a compensatory mechanism of the body to cool down the brain. It’s also a mechanism for maintaining a high level of mental efficiency. Andrew C. Gallup, in his study, highlights the effectiveness of cooling down via external cooling or nasal breathing as substitutes for yawning. He highlights that both options help to reduce yawns and provide a means to tackle the issue.

Psychological Factors

There are psilocybin facilitators who consider yawning as an indication of individual response to high doses. Most facilitators in psilocybin retreats like to start by dosing their patients with 0.5g of shrooms. This strategy helps them gauge their response and also determine how they will respond when given a higher dose.

If small doses cause intense yawning, it may be an indication that the person is influenced by psychological factors like anxiety, excitement, and anticipation that relate to the journey. Also, it’s likely that yawning could be a sign of discomfort. Once the facilitator observes any of these effects, even after a small dose, they usually prepare a pumpkin pie. This could be taken right before a high-dose mushroom experience.

Basically, the seeds of pumpkin are rich in magnesium, which is vital in regulating blood pressure and electrolyte balance, both of which reduce symptoms of anxiety and stress. Another thing to note is that the seeds of pumpkin are rich in tyrosine and tryptophan, both of which are precursors of dopamine and serotonin and play a role in mood regulation.

Increased Dopamine and Serotonin Levels

As earlier mentioned, psilocin and psilocybin both interact with serotonin receptors. In a placebo-controlled trial with citalopram, which is an antidepressant, yawning was a major side effect that was observed. There are now researches that link yawning with levels of dopamine.

There are other neurotransmitters that can influence yawning. These neurotransmitters are serotonin, acetylcholine, norepinephrine, nitric oxide, oxytocin, ɣ-aminobutyric acid, and a range of other neuropeptides. All of these have been shown to increase yawning via similar mechanisms.

How to Prevent or Reduce Yawning During a Trip

According to anecdotal results, there’s a link between yawning frequency and dosage. If you yawn excessively, and it starts to cause you discomfort, you might need to ingest lower doses of the psychedelic mushrooms.

Another approach to consider is to lemon tek your shrooms. This involves grinding the shrooms into smaller pieces and mixing them with lemon or lime juice. Allow the mixture for 20 minutes, with repeated stirring every 5 minutes, to allow the effective conversion of psilocybin to psilocin in the acidic substance. To prevent the psilocin from oxidizing, allow it to sit for more than 30 minutes.

You can directly consume the mixture or dilute it for a milder taste, depending on your preference. Converting psilocybin to psilocin before ingestion makes your tripping experience better because its come-up will be easier and faster on your stomach. Yawning occurs when the initial effects start to kick in, but with this approach, you won’t yawn too frequently.

There are other techniques that you can consider to stop the yawning reflex. Here are two approaches proposed by psychologist Andrew C. Gallup:

  • Pressing a cold compress to your forehead
  • Breathing through the nose

Since yawning is a mechanism the body uses in regulating the temperature of the brain, especially following the failure of regulatory mechanisms, cooling down is a great way to prevent the event. Breathing through the nose is also an approach to stop yawning, and this works by closing the mouth and taking deep breaths. The second method is pressing a cold compress on the forehead because it’s the region that directly influences the temperature of the brain.


Although the absence of a definitive scientific explanation linking mushroom consumption to frequent yawning can be frustrating, there are numerous clinical trials currently studying the potential therapeutic advantages of psilocybin mushrooms. These trials suggest that psilocybin therapy may receive FDA approval for treating resistant depression by 2025, pending the validation of positive results in the largest Phase 3 psilocybin clinical trial.

The FDA’s recent guidance on psychedelic clinical trial design indicates a positive attitude toward further exploration of these substances by the scientific community while complying with governmental regulations.

If you are presently under the influence of mushrooms and have stumbled upon this article seeking reassurance, rest assured that yawning is a common side effect and not a cause for concern. To alleviate any annoyance caused by frequent yawning, refer to the techniques provided in the preceding section. You can also read other articles on our blog at Microdose Bros to learn more about magic mushrooms and other psychedelics.