Category: Understanding Psychedelics

Psychedelics primarily act on the serotonin system, especially the 5-HT2A receptor.
They temporarily quiet the Default Mode Network (DMN) — the part of the brain linked to ego and repetitive thinking. This allows different brain regions to communicate more freely, leading to vivid visuals, emotional breakthroughs, and a sense of unity or interconnectedness.

This same mechanism is why psilocybin is being studied for depression, PTSD, OCD, and addiction — helping the brain “reset” unhealthy neural patterns.