Category:
Microdosing 101
When psilocybin is ingested (from truffles or mushrooms), it converts into psilocin, which binds primarily to serotonin 5-HT2A receptors in the brain.
At microdose levels, this subtly increases connectivity between brain regions, while temporarily quieting the Default Mode Network (DMN)—a network linked to self-critical and repetitive thought patterns.
The result is a gentle “neural reset” effect:
- more flexibility in thinking,
- better emotional regulation,
- improved presence and flow states.
Research also suggests psilocybin promotes neuroplasticity—encouraging new connections between neurons—especially when paired with mindfulness, exercise, and journaling.
