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Psilocybin for Treatment-Resistant Depression: What the New NHS Trial Actually Found By Joseph Santiago, founder of Microdose Bros. Connect with me on LinkedIn A new trial in Nature Medicine tested psilocybin-assisted therapy inside England’s National Health Service, on people who had been depressed for about 20 years on average and hadn’t been helped by the […]

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Psilocybin and Depression: What the UK’s Landmark Trial Actually Found For most of the last fifty years, psilocybin has lived in a strange limbo. Ancient medicine to some cultures, a countercultural symbol to others, a banned substance to governments, and — for a very long time — almost impossible to study seriously. That’s shifting again. […]

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Written by Joseph Santiago Exploring the science behind psychedelics, cannabis use disorder, and my personal journey after nearly 30 years of daily cannabis use. Many people start using cannabis for good reasons. Some use it to relax after a stressful day. Others use it to support sleep, reduce discomfort, spark creativity, or simply enjoy a deeper […]

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A Single Psilocybin Session Offers Lasting Relief for Cancer Patients, Study Finds By Joseph Santiago For decades, patients facing cancer have not only battled the disease itself but also the crushing weight of anxiety, depression, and existential distress that so often accompany it. Traditional treatments for these psychological burdens—talk therapy, antidepressants, anti-anxiety medications—offer uneven relief. […]

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