One of the common side effects of psilocybin magic mushrooms, especially after ingestion, is nausea. It can get really unpleasant in some cases and cause stomach pains, GI distress, and vomiting. These effects are mostly due to the presence of indigestible chitin, which can cause an immune response and inflammation.

To help ease digestion, most people tend to boil mushrooms so that the chitin can break down. However, this is not done with magic mushrooms because heat can degrade the psychoactive compounds. The good thing is that there are different methods to enhance the digestion of chitin and fight nausea.

In this article, we’ll take you through some of the strategies that you should try to minimize nausea. Continue reading to find out more.

The Lemon Tek

To date, no one knows the actual source of Lemon Tek. Across some of the most popular platforms today, like Quora, Erowid, and Reddit, you’ll find different variations of this method of preparing mushrooms. The good thing is that the process is pretty straightforward, and all you need is to grind dried mushrooms and soak them in lemon juice for up to fifteen minutes.

Many anecdotal reports claim that the method is great for people who want to prevent nausea. It’s important to note that there is no research to show how Lemon Tek actually works. However, there are many indirect studies that provide sufficient evidence to support its mechanism.

Converting dried mushrooms to a fine powder simulates the teeth is meant to achieve. Basically, breaking down the chitinous mushroom flesh helps to ease the burden on your stomach. Secondly, soaking the powdered mushroom in lemon juice simulates the process of digestion. Remember that the pH of the stomach is between 1.5 to 3.5, and that of lemon juice is between 2 and 2.6. Basically, lemon juice provides the acidic environment needed for converting psilocybin to psilocin.

Even though psilocin and psilocybin occur naturally in mushrooms, psilocybin occurs in a much higher concentration. It is then converted into psilocin by the alkaline phosphatase and the stomach’s acidic environment. The process of this conversion is known as dephosphorylation. A key thing to note is that psilocin is the compound responsible for the psychoactive effects of magic mushrooms.

It is generally believed that nausea is triggered by the conversion of psilocybin to psilocin. However, Lemon Tek helps people avoid this effect.

Mushroom Tea

Mushroom tea and Lemon Tek have similar methods of preparation, as the magic mushrooms are first converted to a fine powder. As mentioned earlier, this helps one to avoid the stress from the mechanical breakdown of chitin. The powdered mushroom is then placed in hot water for up to 25 minutes to bring psilocybin into the solution.

The solution is then strained out to make it more optimal for people who are susceptible to nausea. It’s worth noting that this method of preparation brings a faster onset of action and minimizes nausea sensation, unlike directly ingesting or chewing magic mushrooms.

Long Mastication Process

For many, this is the easiest way to consume magic mushrooms. It basically involves taking a measured dose of the mushroom and chewing it for up to 30 minutes before swallowing. The idea is that chewing for a long period ensures the maximization of chitinase. This is an enzyme that breakdown chitin.

Mastication helps reduce nausea while allowing users to enjoy a quick onset of effects, unlike the direct chewing and ingestion method.


For a while now, ginger has been considered to be a potent antiemetic agent, and this is in addition to other medicinal effects it offers. It helps in fighting the symptoms of nausea and vomiting. Interestingly, ginger is considered to be a safe and effective treatment option for symptoms of nausea and vomiting. It is mostly applied in patients undergoing chemotherapy and pregnant women.

The antiemetic effect of ginger is due to the presence of shogaol and gingerol. These are phytochemicals that act on the serotonergic system, particularly the 5-HT3 and 5-HT4 receptors. They also act on some cholinergic receptors.

With that said, it’s worth noting that combining fresh or raw ginger with magic mushroom preparations help in reducing the symptom of nausea.


Reducing nausea is one of the main components of risk reduction, but many people overlook it. It goes beyond getting a positive set and setting. Even though nausea may be a benign side effect, it’s important to always have it in mind that it can alter your desired psychedelic experience.

The good news is that you can easily fight these side effects by ensuring proper preparation and using the right antiemetic. We have highlighted the approaches that you should consider to help improve your psychedelic experience with psilocybin and avoid nausea and vomiting.

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