Psilocybin for Treatment-Resistant Depression: What the New NHS Trial Actually Found By Joseph Santiago, founder of Microdose Bros. Connect with me on LinkedIn A new trial in Nature Medicine tested psilocybin-assisted therapy inside England’s National Health Service, on people who had been depressed for about 20 years on average and hadn’t been helped by the […]
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If you’ve ever taken magic mushrooms or magic truffles two days in a row and felt… almost nothing the second time, you’ve already met psilocybin tolerance firsthand. It’s one of the most consistent things about this compound, and also one of the most misunderstood. People assume tolerance works like it does with caffeine, marijuana or […]
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Can Psilocybin Change How We Learn From Bad Experiences? New Research Says Maybe If you’ve spent any time in psychedelic spaces, you’ve heard some version of this story: someone takes a journey, and afterward, an old belief they’d carried for years just… loosens. A fear that felt permanent suddenly looks negotiable. A relationship they’d been […]
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Are Psychedelics Medicine? It’s Complicated Written by Joseph Santiago Ask someone who’s had a real psychedelic experience whether it was “medicine,” and you’ll usually get a pause before the answer. Not because they’re unsure it helped them, plenty of people will tell you it did, but because “medicine” feels like too small a word for […]
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Psychedelic Honey: What to Do With Your Mushroom Harvest If you’ve ever grown your own magic mushrooms, you know the strange feeling of ending up with more than you expected. A good flush can leave you staring at a pile of dried caps wondering what you’re actually going to do with all of it. Eating […]
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