In Silicon Valley, financiers and tech entrepreneurs, now psychonauts, believe that Microdosing psychedelics help them in many ways. The main psychedelic they take is LSD, which they believe increases productivity and creativity in small doses. In Sun Valley, several private retreats focus on tripping on the Amazonian elixir ayahuasca or MDMA. This is a common sight in most backyard barbecues, and the key is not to include kids. 

Another interesting one is in Southampton, where soccer moms microdose psilocybin mushrooms for different reasons. These are only some of the well-known stories, and there are many others. However, there’s a weirder and wilder new substance catching the attention of many. That’s a toad, 5-MeO-DMT (5-methoxy-N, N-dimethyltryptamine), Bufo, or DMT.

What Exactly are they Smoking?

DMT is the venom found in Bufo alvarius, the Sonoran desert toad. The venom is rich in 5-MeO-DMT molecules, a potent psychotropic drug. This substance has been obscure for many years, even though people constantly take it. It was this way until 2011, when the U.S government included it in the list of controlled substances.

Today, the Sonoran desert mostly lives under the Mexican desert sands for nine months. It can survive the heat and harsh weather conditions and only come out during the winter rains. The toad comes out during this time for a Caligula-like orgy of fornicating and eating.

But how was the venom first discovered? The toad has glands on the side of its legs and neck. This gland is a defensive mechanism that emits toxic venom at the sight of a predator.

Hunters catch the toad by using bright flashlights to freeze them. They then milk out the venom from the parotid glands and leave it to dry. The dried venom turns to flaky crystals, containing only 5-MeO-DMT, without any toxin.

How Does Smoking Toad Venom Work?

At a dose of 50mg, people smoke the dried substance using a glass pipe. They inhale the substance for at least 10 seconds and hold the vapor for several seconds. The effect of the substance is intense, and people feel it immediately.

Toad venom is rich in 5-MeO-DMT, a substance like psychedelics like psilocybin and LSD. 5-Meo-DMT binds to serotonin receptors, the happiness chemical that sends information to the brain for mood stability. This is the psychedelic mechanism of action of the substance when vaporized or smoked.

The drug is formulated traditionally by a series of dehydration processes on the venom of the Sonoran Desert toad. However, recent manufacturing processes now employ synthetic methods in producing the drug.

Further research is ongoing to understand the mechanisms of action of 5-MeO-DMT fully. However, a tryptamine like LSD and psilocybin can create a sense of ego dissolution, euphoria, and unity. Although the drug tends to act faster with more intensity, the duration of action is shorter. 5-MeO-DMT duration of action is only 20 minutes, compared to psilocybin and other psychedelics that last for hours.

What is the Toad Venom Trip Like?

Different users describe the trip in many ways. Here’s what David E. Carpenter has to say to understand the trip fully. He is a journalist covering breakthroughs and trends in psychoactive drugs for Forbes. David has been gathering data from interviews with toad venom users for his book:

5 & I: A Journey Into The Mysterious World of 5-MeO-DMT, The Most Powerful Psychoactive Drug On The Planet

According to him, how the substance causes a shift in people’s perspective is surprising. Many people describe the drug’s effect as a gateway to the sacred. Other people describe it as a way to connect with other levels of consciousness. They claim to have a better understanding of the universe.

In general, most reports describe the trip as unitary consciousness and oneness. Reports also describe toad venom as a class on its own and don’t compare to other psychoactive substances. That is why they call it the most powerful psychoactive drug on earth.

Toad Venom Safety

There’re always some risks that come with using drugs, and toad venom is no exception. Most psychedelics have a low-risk profile regarding the risk of addiction, overdose, or death. Regarding the intensity of experience, 5-MeO-DMT has a higher risk than psilocybin and other psychedelics.

Most people vape or smoke toad venom, but there are other ways to take the substance. People can take it orally, sublingually, or through injections. However, you can only feel the strongest effect when you vape or smoke the substance.

Is it Legal?

Toad venom is a Schedule I controlled drug in the U.S., but the drug is legal in Mexico and Canada.

When Did Smoking DMT Become Popular?

DMT was first synthesized in 1936, but modern use only started in 1984, according to Matthew W. Johnson. The popularity of the substances is due to the increasing awareness of their effect over the past few years. Different factors also contribute to the increasing popularity, and the internet has a role in it.

The recent surge of interest in toad venom is alarming. We can link it to the drug’s fast onset and short duration. Most people prefer something that gives effect within a few minutes rather than hours. DMT allows people to experience its effects within 15 minutes, which is why people are running to it. In addition, its therapeutic benefits also make the substance popular.

Toad Venom and Mental Health Problems

Research on 5-MeO-DMT by Johns Hopkins, Maastricht University, shows its potential for treating different mental illnesses. This includes PTSD, substance use disorder, end-of-life fear, anxiety, and depression.

A drug is an effective tool for mental health, especially when combined with psychotherapy. Beckley Psytech and G.H. Research are performing separate clinical trials to examine its effectiveness on treatment-resistant depression.

There’s a need for more research on toad venom, but 5-MeO-DMT can likely help psychiatric disorders like other psychedelics.

Final Thoughts

You might also be wondering how the popularity of toad venom will affect the toad population. It’s not so nice because there’s a worry that the Bufo alvarius toad may become endangered. That is why people are advised to go for the synthesized drug version since they are not different.

Alternatively, you can continue taking other psychedelic substances like magic truffles. For more information, visit our blog about magic truffles, psychedelics, and Microdosing.    

Buy magic truffles from MicrodoseBros.com. These magic truffles contain high quantities of visionary psilocybin.

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